nasdaq:adap
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adaptimmunellc.applytojob.com
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adaptimmunellc.applytojob.com
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Jul 30th, 2019 12:00AM
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Qualification Validation Associate
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Open
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CMC
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Stevenage
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Hertfordshire
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GBR
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Primary ResponsibilityAdaptimmune is seeking a Quality Validation Associate within the Quality unit to primarily focus on the qualification and validation lifecycle of equipment, utilities, systems, and processes for the manufacturing of vector which is a starting material used in the manufacture of Adaptimmune T-cell drug products. This role will also manage activities at the sites of manufacture including the management of change controls and the application of Quality risk management principles. Key ResponsibilitiesDefine Validation/Qualification deliverables including, but not limited to, requirements documents, functional and design specifications, qualification protocols (IQ/OQ/PQ), and summary reports.Develop and author installation/operational qualification protocols and equipment performance/process validation protocols.Execute Validation/Qualification Protocols, including external party supervision, identification and resolution of deviations and technical issues related to equipment, utilities, automation, and cleaning validation.Manage the re-qualification program according to Adaptimmune policiesPerform periodic review of equipment and systems according to Adaptimmune policiesManage the execution of aseptic process validation activities including authoring protocols, evaluating process and assay data, investigating protocol deviations and acceptance criteria failures, and compiling final summary reports. Coordinate validation projects with cross-functional teams including quality assurance, manufacturing operations, process development, quality control, etc.Act as quality oversight for calibration and maintenance activitiesAssist in the development and maintenance of various systems within the Quality unit including preparation of SOPs, documentation control support and implementation and management of the change control system. Punctual support to the quality unit depending on workload (material release, document issuing …)Assist in risk assessments using a variety of tools, e.g. FMEA and HACCP.Participate in efforts to identify opportunities for and to implement continuous improvement of practices related to validation. Qualifications & ExperienceRequiredBSc or MSc degree in life science or engineering Previous experience in validation, technical operations, or quality assurance.within a Pharmaceutical/Biotech companyMust have experience in the writing of technical documentsMust have experience of creation of experimental design and be motivated to do hands on testing of equipmentMust have knowledge of cGMP, GDP and best industry practices.Must have good communication skillsDesirableExperience in validations, including but not limited to product, process, equipment, test methods, DOE, cleaning and software validationsPrevious experience in a GMP or GLP environmentPrevious experience in pharmaceutical/biotech manufacturingKnowledge of Calibration and Maintenance Skills & CompentenciesRequiredGood written and verbal communication skillsMust be rigorous, organised and have attention to detailsMust be able to work well on cross-functional teams, as well as perform independently.Must be self-motivated and have good interpersonal skillsDesirableAble to manage multiple prioritiesStrong organizational and project planning skills. Other RequirementsDomestic travel required (up to 5%)
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Jul 29th, 2019 10:05PM
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Jul 29th, 2019 10:05PM
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Adaptimmune Therapeutics
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Health Care
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Pharmaceuticals & Biotechnology
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nasdaq:adap
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adaptimmunellc.applytojob.com
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adaptimmunellc.applytojob.com
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Jul 30th, 2019 12:00AM
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Scientist (T-cell Immunology)
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Open
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Research
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Abingdon
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Oxfordshire
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GBR
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Primary ResponsibilityAdaptimmune are Seeking a highly motivated junior scientist with relevant industrial experience, and a good background in T cell immunology to join the dynamic Cell Research team at Adaptimmune. The Cell Research group is responsible for proposing and testing second generation T cell products for improvements in T cell product efficacy and persistence. Desirable skills for this group include primary cell culture, lentiviral transfection, flow cytometry and cytotoxicity assays including, but not limited to Incucyte.The successful candidate would have an MSc or BSc with relevant experience in T cell immunology to contribute to our dynamic, exciting culture that embraces teamwork and innovation. The purpose of this role is to primarily conduct scientific experiments as necessary within our dedicated scientific team. You will work under the supervision of more experienced Senior and Principal scientists to contribute to the development of various next generation cellular therapies. You will also be required to interpret scientific results under the supervision of a senior scientist and to present your conclusions in group meetings.Please note : Hep B Vaccination (with documentary evidence of successful vaccination titre) is preferably required for this position. If not already vaccinated, Hepatitis B vaccination will be required and costs covered by Adaptimmune. Key Responsibilities70% the design and execution of T cell assays including but not limited to cytotoxicity, cytokine/chemokine measurements, and proliferation25% data analysis and communication of conclusions5% maintaining knowledge latest scientific literature relevant to cellular therapies, genetic engineering, and T cell biology Qualifications & ExperienceRequiredMSc or BSc with relevant industrial experience in immunologyDesirableProficiency in the use of software to support data analysis such as FlowJo, FACSDiva, GraphPad Prism, as well as Microsoft Office (Excel, PowerPoint, Word, Outlook) Skills & CompetenciesRequiredMulti-colour flow cytometry (knowledge of T cell subsets)Mammalian cell culturePrimary T cell assays (expansion, proliferation and cytotoxicity)Knowledge of the latest scientific literature relevant to cellular therapies, cell engineering, and T cell biologyDesirablePrior experience with generation of retroviral/lentiviral vectors and transduction of target cells
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Jul 29th, 2019 10:05PM
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Jul 29th, 2019 10:05PM
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Adaptimmune Therapeutics
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Health Care
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Pharmaceuticals & Biotechnology
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nasdaq:adap
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adaptimmunellc.applytojob.com
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adaptimmunellc.applytojob.com
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Jul 30th, 2019 12:00AM
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Scientist/Senior Scientist (T-cell Immunology) - Maternity cover (12mths contract)
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Open
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Research
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Abingdon
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Oxfordshire
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GBR
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Primary ResponsibilityAdaptimmune are seeking a highly motivated, recently qualified PhD with a good background in T cell immunology to join the dynamic Cell Research team at Adaptimmune. The Cell Research group is responsible for proposing and testing second generation T cell products for improvements in T cell product efficacy and persistence. The required skills to perform the role include primary cell culture, lentiviral transfection, ELISA, flow cytometry and cytotoxicity assays including, but not limited to Incucyte.The successful candidate would have a PhD in T cell immunology and contribute to our dynamic, exciting culture that embraces teamwork and innovation. The purpose of this role is to primarily conduct research projects independently or with other senior scientists, as necessary, within our dedicated scientific team. You will work initially under the supervision of more experienced Senior and Principal scientists to contribute to the development of various next generation cellular therapies. You will also be required to interpret scientific results, present your conclusions and strategies for future work in group meetings.Please note : Hep B Vaccination (with documentary evidence of successful vaccination titre) is required for this position. Key Responsibilities60% the design and execution of T cell assays including but not limited to cytotoxicity, proliferation cytokine/chemokine measurements and flow cytometry30% data analysis and communication of conclusions10% maintaining knowledge latest scientific literature relevant to cellular therapies, genetic engineering, and T cell biology Qualifications & ExperienceRequiredPhD with relevant experience in T cell immunologyProficiency in the use of software to support data analysis such as FlowJo, FACSDiva, GraphPad Prism, as well as Microsoft Office (Excel, PowerPoint, Word, Outlook)Hep B Vaccination Skills & CompetenciesRequiredMulti-colour flow cytometry (knowledge of T cell subsets)Soluble mediator detection assays (ELISA, MAGPIX, MSD)Mammalian cell culturePrimary T cell assays (expansion, proliferation and cytotoxicity)Generation of retroviral/lentiviral vectors and transduction of target cellsKnowledge of the latest scientific literature relevant to cellular therapies, cell engineering, and T cell biology
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Jul 29th, 2019 10:05PM
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Jul 29th, 2019 10:05PM
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Adaptimmune Therapeutics
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Health Care
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Pharmaceuticals & Biotechnology
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nasdaq:adap
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adaptimmunellc.applytojob.com
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adaptimmunellc.applytojob.com
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Jul 31st, 2019 12:00AM
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Qualification Validation Associate
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Open
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CMC
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Stevenage
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Hertfordshire
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GBR
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Primary ResponsibilityAdaptimmune is seeking a Quality Validation Associate within the Quality unit to primarily focus on the qualification and validation lifecycle of equipment, utilities, systems, and processes for the manufacturing of vector which is a starting material used in the manufacture of Adaptimmune T-cell drug products. This role will also manage activities at the sites of manufacture including the management of change controls and the application of Quality risk management principles. Key ResponsibilitiesDefine Validation/Qualification deliverables including, but not limited to, requirements documents, functional and design specifications, qualification protocols (IQ/OQ/PQ), and summary reports.Develop and author installation/operational qualification protocols and equipment performance/process validation protocols.Execute Validation/Qualification Protocols, including external party supervision, identification and resolution of deviations and technical issues related to equipment, utilities, automation, and cleaning validation.Manage the re-qualification program according to Adaptimmune policiesPerform periodic review of equipment and systems according to Adaptimmune policiesManage the execution of aseptic process validation activities including authoring protocols, evaluating process and assay data, investigating protocol deviations and acceptance criteria failures, and compiling final summary reports. Coordinate validation projects with cross-functional teams including quality assurance, manufacturing operations, process development, quality control, etc.Act as quality oversight for calibration and maintenance activitiesAssist in the development and maintenance of various systems within the Quality unit including preparation of SOPs, documentation control support and implementation and management of the change control system. Punctual support to the quality unit depending on workload (material release, document issuing …)Assist in risk assessments using a variety of tools, e.g. FMEA and HACCP.Participate in efforts to identify opportunities for and to implement continuous improvement of practices related to validation. Qualifications & ExperienceRequiredBSc or MSc degree in life science or engineering Previous experience in validation, technical operations, or quality assurance.within a Pharmaceutical/Biotech companyMust have experience in the writing of technical documentsMust have experience of creation of experimental design and be motivated to do hands on testing of equipmentMust have knowledge of cGMP, GDP and best industry practices.Must have good communication skillsDesirableExperience in validations, including but not limited to product, process, equipment, test methods, DOE, cleaning and software validationsPrevious experience in a GMP or GLP environmentPrevious experience in pharmaceutical/biotech manufacturingKnowledge of Calibration and Maintenance Skills & CompentenciesRequiredGood written and verbal communication skillsMust be rigorous, organised and have attention to detailsMust be able to work well on cross-functional teams, as well as perform independently.Must be self-motivated and have good interpersonal skillsDesirableAble to manage multiple prioritiesStrong organizational and project planning skills. Other RequirementsDomestic travel required (up to 5%)
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Jul 30th, 2019 10:05PM
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Jul 30th, 2019 10:05PM
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Adaptimmune Therapeutics
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Health Care
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Pharmaceuticals & Biotechnology
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nasdaq:adap
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adaptimmunellc.applytojob.com
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adaptimmunellc.applytojob.com
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Aug 1st, 2019 12:00AM
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Scientist (T-cell Immunology)
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Open
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Research
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Abingdon
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Oxfordshire
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GBR
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Primary ResponsibilityAdaptimmune are Seeking a highly motivated junior scientist with relevant industrial experience, and a good background in T cell immunology to join the dynamic Cell Research team at Adaptimmune. The Cell Research group is responsible for proposing and testing second generation T cell products for improvements in T cell product efficacy and persistence. Desirable skills for this group include primary cell culture, lentiviral transfection, flow cytometry and cytotoxicity assays including, but not limited to Incucyte.The successful candidate would have an MSc or BSc with relevant experience in T cell immunology to contribute to our dynamic, exciting culture that embraces teamwork and innovation. The purpose of this role is to primarily conduct scientific experiments as necessary within our dedicated scientific team. You will work under the supervision of more experienced Senior and Principal scientists to contribute to the development of various next generation cellular therapies. You will also be required to interpret scientific results under the supervision of a senior scientist and to present your conclusions in group meetings.Please note : Hep B Vaccination (with documentary evidence of successful vaccination titre) is preferably required for this position. If not already vaccinated, Hepatitis B vaccination will be required and costs covered by Adaptimmune. Key Responsibilities70% the design and execution of T cell assays including but not limited to cytotoxicity, cytokine/chemokine measurements, and proliferation25% data analysis and communication of conclusions5% maintaining knowledge latest scientific literature relevant to cellular therapies, genetic engineering, and T cell biology Qualifications & ExperienceRequiredMSc or BSc with relevant industrial experience in immunologyDesirableProficiency in the use of software to support data analysis such as FlowJo, FACSDiva, GraphPad Prism, as well as Microsoft Office (Excel, PowerPoint, Word, Outlook) Skills & CompetenciesRequiredMulti-colour flow cytometry (knowledge of T cell subsets)Mammalian cell culturePrimary T cell assays (expansion, proliferation and cytotoxicity)Knowledge of the latest scientific literature relevant to cellular therapies, cell engineering, and T cell biologyDesirablePrior experience with generation of retroviral/lentiviral vectors and transduction of target cells
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Jul 31st, 2019 10:05PM
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Jul 31st, 2019 10:05PM
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Adaptimmune Therapeutics
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Health Care
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Pharmaceuticals & Biotechnology
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nasdaq:adap
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adaptimmunellc.applytojob.com
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adaptimmunellc.applytojob.com
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Aug 3rd, 2019 12:00AM
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Director, Vector Development
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Open
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Process Development
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Abingdon
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Oxfordshire
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GBR
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Primary Responsibility
This role is to provide strategic and operational leadership to the Vector Development group at Adaptimmune. The scope includes the day to day management of the upstream and downstream process development teams, oversight and review of the Vector Development projects, strategic updating Adaptimmune’s vector development roadmap and interfacing with other key functions (MS&T, Manufacturing, Quality and Regulatory), and especially focusing on the tech transfer of new processes and innovations out of process development.
Key Responsibilities
Day to day management and leadership of the of the bioprocess development function within the vector development team – 20%
Lead project governance of all vector development projects. Provide technical review of experimental designs, results, conclusions and the process development plans of the bioprocess development function within Vector Development – 25%
In conjunction with their team provide strategic direction for vector bioprocessing at Adaptimmune to drive increased process optimisation, process understanding and decreased COGS – 20%
Work collaboratively with the Vector MS&T on the tech transfer of new process into GMP manufacturing – 15%
Manage any outsourced development activities for vector bioprocessing with subcontractors – 20%
Qualifications & Experience
Required
BSc or higher qualification in relevant area.
Experience with bioprocess development in the gene therapy, vaccine and/or biopharmaceutical fields, significant relevant industrial experience is required.
Depth of expertise in people leadership and development is also key to this role.
The role requires a depth of experience in the process development, optimization, scale-up and technology transfer of bioprocesses. The role would lead the vector bioprocess development effort within Vector Development group and would be responsible for the development of the entire bioprocess including the upstream production of the vector and downstream purification and concentration unit operations. Therefore a deep understanding of technologies suitable for scale-up of bioprocesses is required including
bioreactors (suspension or adherent based cell culture),
chromatography
dead-end / tangential flow filtration is required.
significant knowledge and experience of the scale-up and scale-down of upstream and downstream unit operations
Desirable
Experience in live virus or gene therapy product formulation would be an advantage.
Knowledge of viral vector biology and molecular biology would be an advantage but is not essential.
Experience of assisting in the authoring of regulatory submissions (IND/IMPD) would also be a significant advantage.
Experience of BLA/MAA preparation including process understanding, risk assessment and control strategy implementation with any category of biopharmaceutical (recombinant protein, vaccine or an ATMP) would also be an advantage.
Skills & Competencies
Required
The relevant skills and competencies to provide line management of a process development team are necessary. These skills include the ability to, motivate, delegate, and provide personal development insight for direct and indirect reports. Furthermore the ability to simultaneously improve both efficiency and quality within the team are required through driving efficient team work is required.
The role requires an excellent communicator who is able to provide clear messages, both internally and to external partners.
Skills and knowledge relating to the development, scale-up and tech transfer of bioprocesses destined for GMP manufacture are key for this role. These skills should include the ability to critically examine in-process data, evaluating both yield and product quality leading to a risk based approach to further optimise and understand the bioprocess. An attention to detail is also key to enable thorough review of development reports, tech transfer documents and batch records.
Desirable
Knowledge of statistical experimental design (such as DoE) would be a significant advantage.
Decision Making Authority
The responsibility of the role is to provide the leadership of the Vector Development group.
Size and scope of team :4 direct reports and up to 10 indirect reports
Other Requirements
Travel to CMOs and conferences is likely to be required.
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Aug 2nd, 2019 10:04PM
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Aug 2nd, 2019 10:04PM
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Adaptimmune Therapeutics
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Health Care
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Pharmaceuticals & Biotechnology
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nasdaq:adap
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adaptimmunellc.applytojob.com
|
adaptimmunellc.applytojob.com
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Aug 4th, 2019 12:00AM
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Scientist (T-cell Immunology)
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Open
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Research
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Abingdon
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Oxfordshire
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GBR
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Primary ResponsibilityAdaptimmune are Seeking a highly motivated junior scientist with relevant industrial experience, and a good background in T cell immunology to join the dynamic Cell Research team at Adaptimmune. The Cell Research group is responsible for proposing and testing second generation T cell products for improvements in T cell product efficacy and persistence. Desirable skills for this group include primary cell culture, lentiviral transfection, flow cytometry and cytotoxicity assays including, but not limited to Incucyte.The successful candidate would have an MSc or BSc with relevant experience in T cell immunology to contribute to our dynamic, exciting culture that embraces teamwork and innovation. The purpose of this role is to primarily conduct scientific experiments as necessary within our dedicated scientific team. You will work under the supervision of more experienced Senior and Principal scientists to contribute to the development of various next generation cellular therapies. You will also be required to interpret scientific results under the supervision of a senior scientist and to present your conclusions in group meetings.Please note : Hep B Vaccination (with documentary evidence of successful vaccination titre) is preferably required for this position. If not already vaccinated, Hepatitis B vaccination will be required and costs covered by Adaptimmune. Key Responsibilities70% the design and execution of T cell assays including but not limited to cytotoxicity, cytokine/chemokine measurements, and proliferation25% data analysis and communication of conclusions5% maintaining knowledge latest scientific literature relevant to cellular therapies, genetic engineering, and T cell biology Qualifications & ExperienceRequiredMSc or BSc with relevant industrial experience in immunologyDesirableProficiency in the use of software to support data analysis such as FlowJo, FACSDiva, GraphPad Prism, as well as Microsoft Office (Excel, PowerPoint, Word, Outlook) Skills & CompetenciesRequiredMulti-colour flow cytometry (knowledge of T cell subsets)Mammalian cell culturePrimary T cell assays (expansion, proliferation and cytotoxicity)Knowledge of the latest scientific literature relevant to cellular therapies, cell engineering, and T cell biologyDesirablePrior experience with generation of retroviral/lentiviral vectors and transduction of target cells
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Aug 3rd, 2019 10:05PM
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Aug 3rd, 2019 10:05PM
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Adaptimmune Therapeutics
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Health Care
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Pharmaceuticals & Biotechnology
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nasdaq:adap
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adaptimmunellc.applytojob.com
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adaptimmunellc.applytojob.com
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Aug 4th, 2019 12:00AM
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Research Scientist, Translational Sciences
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Open
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Research
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Abingdon
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Oxfordshire
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GBR
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Primary ResponsibilityFunctional Focus: The Translational Sciences group aims to provide an in depth understanding of the mechanisms of tumour response to our SPEAR T-cell therapy. We are looking for a driven individual to fully develop their skillset in order to understand and optimise responses to SPEAR-T cell therapy. Desirable skills include those related to histology and gene/protein expression profiling. The purpose of this role is to primarily conduct scientific experiments as necessary within dedicated scientific and project teams. Whilst initially requiring supervision by a more senior scientist, the job holder will develop further scientific skills to be able to work more independently on routine experiments. The job holder will also be responsible for the interpretation of scientific results under the supervision of a Principal Scientist or Senior Scientist. The scientist may also be involved in one or more support activities to enable the smooth running of the group or laboratory and enabling company functioning toward its goals (e.g. Lab steward role) Performance in this role (including functional and project objectives and behaviours) is expected to be monitored through group performance and stakeholder feedback from peers, senior management and project team members (as outlined in the development framework for this position). Key ResponsibilitiesConducting experiments and supporting colleagues, the group and Adaptimmune projects.In collaboration with the Senior Scientists and Principal Scientists, analyse, summarise and record experimental results and maintain relevant databases and records.Participate in group and project meetings and discussions.Routine lab maintenance. Qualifications & ExperienceRequired:Degree in Life Sciences (minimum B.Sc.) Experience of laboratory procedures.Ability to work independently on routine experiments with limited supervision.Ability to learn and develop in order to work independently on more complex experiments within a reasonable time frame.Desired :Additional post-graduate scientific experience or qualifications, such as an MSc. or PhD Skills & CompetenciesRequiredHistological skills includingFFPE Tissue sectioning using microtome,Special stains (e.g.: Giemsa)ImmunohistochemistryIn situ hybridisation (e.g.: RNAscope)Experience handling human tissue. Ability to follow protocols.Computer literate and ability to familiarise with different IT systems.Excellent numeracy and English language skills (both written and verbal).Excellent communication skills (both written and verbal).Knowledge and skills to use of standard laboratory equipment (such as pipettes, pH meters, centrifuges).Basic experimental design skills (use of controls, etc.) and attention to detail.Good time management and organisational skills.Able to work independently after training.Strong team player but with the ability to work independently as well.DesiredUse of Discovery Ultra Research Instrument (IHC and ISH Platform)Analytical assay validationExperience of immunology and/or cell biologyUnderstanding of Digital Pathology analysis (HALO)Experience working under HTA licence.
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Aug 3rd, 2019 10:05PM
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Aug 3rd, 2019 10:05PM
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Adaptimmune Therapeutics
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Health Care
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Pharmaceuticals & Biotechnology
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nasdaq:adap
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adaptimmunellc.applytojob.com
|
adaptimmunellc.applytojob.com
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Oct 9th, 2018 12:00AM
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Clinical Project Manager– Associate Director
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Open
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Clinical Development
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Abingdon
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Oxfordshire
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GBR
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Primary Responsibility
The Associate Director level Clinical Scientist role is an EU role, based in the UK. The role provides scientific input and oversight, as well as leadership and management of cross-functional execution of clinical studies, within Adaptimmune’s programs.
The Clinical Scientist will be responsible for EU clinical trial delivery including the planning, management and reporting of trials in accordance with company plans/objectives, GCP, local country requirements and company standard operating procedures. This includes writing and/or reviewing protocols, interacting with sites for feasibility assessment, site selection, start up, study conduct, data cleaning, data review, and study close-out, for one or more clinical trials.
Key Responsibilities
Support study design, translate scientific imperative into operational delivery of trials. Review and/or writing of study concept, protocol, study plans, IP management plans, CSRs
Lead the cross-functional Study Conduct Team – drive operational delivery and facilitate issue resolution
Plan timelines, conduct study feasibility, risk assessment/management and contingency planning. Ensure timelines are communicated to all personnel assigned to the study (including vendors)
Plan and/or conduct site evaluation and initiation; develop and maintain effective relationships with clinical sites globally
Provide guidance on protocol and procedures in the development of eCRF design
Review monitoring visit reports; liaise with monitors to understand any trends on data management issues/ICF issues/study binder issues/site staff issue to develop solutions
Review clinical trial data - monitor data quality and ensure appropriate quality measures are in place
Ensure consistency of study execution across studies to facilitate data analysis and regulatory filing
Study specific vendor interaction and coordination
Liaise with clinical drug supply/manufacturing to ensure co-ordination for trial subjects
Maintain TMF and ensure inspection readiness
Proactive stakeholder management and communication of progress and issues
Qualifications & Experience
Required:
Minimum of a BA/BS in Life Sciences Degree
Previous leadership in a matrix environment
Extensive experience in clinical project management of industry-sponsored clinical trials. Experience with biologics or cell and gene therapy is a plus
Strong knowledge of clinical operations and the regulatory process - experience independently running/managing multiple clinical trials preferably within the oncology area
EDC including trial management, data review, issuing and resolving queries, CRF design/review/ approval
Prior experience with clinical protocol development and/or regulatory submissions and management
Desirable:
Additional post-graduate scientific experience or qualifications, such as an M.Sc. or PhD
Skills & Competencies
Describe required and desirable skills and competencies needed to successfully perform the role.
Strong interpersonal and communication skills (both spoken and written) – with ability to effectively communicate on project planning, progress, tracking etc.
Strong relationship building skills to work effectively with others in various disciplines and levels
Strong leadership and negotiation skills with ability to employ different styles and/or strategies depending on team- members and situations
Proven ability to manage multiple, complex and competing priorities to effective and efficient conclusion
Project experience leading cross-functional teams in a matrix environment
Experience working cross-culturally a plus
Ability to operate strategically and tactically
Sense of urgency and ability to work effectively to timelines
Highly motivated, independent and a self-starter
Decision Making Authority
Study execution decisions – including planning and risk mitigation. Decisions impacting clinical trial delivery, speed, quality and cost.
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Oct 8th, 2018 10:15PM
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Oct 8th, 2018 10:15PM
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Adaptimmune Therapeutics
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Health Care
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Pharmaceuticals & Biotechnology
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nasdaq:adap
|
adaptimmunellc.applytojob.com
|
adaptimmunellc.applytojob.com
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Oct 9th, 2018 12:00AM
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Director of Project Management - Maternity Cover Contract
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Open
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Project, Portfolio Management and Business Operations
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Abingdon
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Oxfordshire
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GBR
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Primary Responsibility
Provides strategic leadership and operational management to end-to end projects to ensure the effective progression of projects within Adaptimmune’s global portfolio, from pre-candidate selection to support of late stage clinical projects/commercialization.
Provides strong leadership to project teams to:
Set strategic direction and articulate the value proposition for the potential product,
Turn strategy into clear, coherent, yet flexible development plans,
Identify and resolve key issues,
Execute on agreed upon project deliverables
Key Responsibilities
Manages projects of varying complexity and/or multiple projects independently
Develops and coordinates resource planning across functions to assure that adequate resources are being applied to the project
Maintains high level and detailed timelines, assures consistency with input from the functional departments, and assures that the functional timelines are aligned with global project timelines
Tracks the various parts of the timeline and brings issues to the functional leader’s attention. Participates in resolution, and updates timeline on an on-going basis
Works with other team members to ensure that project teams meet their objectives on time and on budget.
Works with functional leaders to ensure positive team spirit and high functioning team
Supports functional leader in leading Project Team meetings
Ensures that key issues are resolved within the team(s) or are elevated to management for resolution
Prepares monthly progress reports and ad hoc reports as required
Identifies project risks with input from functional leaders, and supports resolution of project issues
Ensures that decisions made at project team meetings are assessed as to their impact on the current plan, budget and available resources.
Ensures that team recommendations related to project direction are endorsed by appropriate Governance Bodies
Recommends and implements best practices across project teams e.g., resource capacity planning, project risk management, team performance, timeline development, portfolio management
Participates in development of Project Management tools, templates and processes
Presents updates to Senior leadership as well as colleagues on a regular basis
Qualifications & Experience
Required:
Bachelor’s degree in healthcare related area or business,
Extensive Pharmaceutical experience (preferably in both small and larger companies)
Solid experience of drug development project management
Desirable:
MSc/ MBA or PhD preferred
PMP certification
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Oct 8th, 2018 10:15PM
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Oct 8th, 2018 10:15PM
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Adaptimmune Therapeutics
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Health Care
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Pharmaceuticals & Biotechnology
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