| Ticker Symbol | Entity Name | Form Type | Access Number | Period | As Of Date | Filing Date | Institution Name | CIK | Name of Issuer | Title of Class | CUSIP | Value | SHRS or PRN Amount | SHRS or PRN Type | PUT_CALL | Investment Discretion | Other Manager | Voting Authority Sole | Voting Authority Shared | Voting Authority None | Date Added | Date Updated | Company Name | Sector | Industry |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| nasdaq:agio | nasdaq:agio Shareholders | 13F-HR | 0001145443-22-000169 | Mar 31st, 2022 12:00AM | May 20th, 2022 12:00AM | May 20th, 2022 12:00AM | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 928047 | AGIOS PHARMACEUTICALS INC | COM | 00847X104 | 1605 | 54863 | SH | DFND | 1,2,5,6 | 0 | 0 | 54863 | May 21st, 2022 01:09AM | May 21st, 2022 01:09AM | Agios Pharmaceuticals | Health Care | Pharmaceuticals & Biotechnology | |
| nasdaq:agio | nasdaq:agio Shareholders | 13F-HR | 0000950123-22-006648 | Mar 31st, 2022 12:00AM | May 20th, 2022 12:00AM | May 20th, 2022 12:00AM | INTERNATIONAL BIOTECHNOLOGY TRUST PLC | 942257 | AGIOS PHARMS. | COM | 00847X104 | 707 | 21500 | SH | SOLE | 21500 | 0 | 0 | May 21st, 2022 01:08AM | May 21st, 2022 01:08AM | Agios Pharmaceuticals | Health Care | Pharmaceuticals & Biotechnology | ||
| nasdaq:agio | nasdaq:agio Shareholders | 13F-HR | 0001567619-22-011132 | Mar 31st, 2022 12:00AM | May 18th, 2022 12:00AM | May 18th, 2022 12:00AM | NOMURA HOLDINGS INC | 1163653 | AGIOS PHARMACEUTICALS INC | CMN | 00847X104 | 391 | 13000 | SH | SOLE | 4 | 13000 | 0 | 0 | May 19th, 2022 01:13AM | May 19th, 2022 01:13AM | Agios Pharmaceuticals | Health Care | Pharmaceuticals & Biotechnology | |
| nasdaq:agio | nasdaq:agio Shareholders | 13F-HR/A | 0001166588-22-000018 | Mar 31st, 2022 12:00AM | May 18th, 2022 12:00AM | May 18th, 2022 12:00AM | BNP PARIBAS ARBITRAGE, SA | 1166588 | Agios Pharmaceuticals Inc | Equity | 00847X104 | 821135 | 28208 | SH | DFND | 1 | 0 | 28208 | 0 | May 19th, 2022 01:12AM | May 19th, 2022 01:12AM | Agios Pharmaceuticals | Health Care | Pharmaceuticals & Biotechnology | |
| nasdaq:agio | nasdaq:agio Shareholders | 13F-HR | 0000093751-22-000509 | Mar 31st, 2022 12:00AM | May 16th, 2022 12:00AM | May 16th, 2022 12:00AM | STATE STREET CORP | 93751 | AGIOS PHARMACEUTICALS INC | COM | 00847X104 | 92759 | 3186513 | SH | DFND | 19,2,20,5,8 | 3063937 | 1000 | 121576 | May 17th, 2022 01:26AM | May 17th, 2022 01:26AM | Agios Pharmaceuticals | Health Care | Pharmaceuticals & Biotechnology | |
| nasdaq:agio | nasdaq:agio Shareholders | 13F-HR | 0000080255-22-002340 | Mar 31st, 2022 12:00AM | May 16th, 2022 12:00AM | May 16th, 2022 12:00AM | PRICE T ROWE ASSOCIATES INC /MD/ | 80255 | AGIOS PHARMACEUTICALS INC | COMM STK | 00847X104 | 78644 | 2701625 | SH | SOLE | 657674 | 0 | 2043951 | May 17th, 2022 01:26AM | May 17th, 2022 01:26AM | Agios Pharmaceuticals | Health Care | Pharmaceuticals & Biotechnology | ||
| nasdaq:agio | nasdaq:agio Shareholders | 13F-HR | 0000072971-22-000135 | Mar 31st, 2022 12:00AM | May 16th, 2022 12:00AM | May 16th, 2022 12:00AM | WELLS FARGO & COMPANY/MN | 72971 | AGIOS PHARMACEUTICALS INC | COM | 00847X104 | 10 | 337 | SH | DFND | 48 | 337 | 0 | 0 | May 17th, 2022 01:24AM | May 17th, 2022 01:24AM | Agios Pharmaceuticals | Health Care | Pharmaceuticals & Biotechnology | |
| nasdaq:agio | nasdaq:agio Shareholders | 13F-HR | 0000072971-22-000135 | Mar 31st, 2022 12:00AM | May 16th, 2022 12:00AM | May 16th, 2022 12:00AM | WELLS FARGO & COMPANY/MN | 72971 | AGIOS PHARMACEUTICALS INC | COM | 00847X104 | 19 | 642 | SH | DFND | 24 | 642 | 0 | 0 | May 17th, 2022 01:24AM | May 17th, 2022 01:24AM | Agios Pharmaceuticals | Health Care | Pharmaceuticals & Biotechnology | |
| nasdaq:agio | nasdaq:agio Shareholders | 13F-HR | 0000072971-22-000135 | Mar 31st, 2022 12:00AM | May 16th, 2022 12:00AM | May 16th, 2022 12:00AM | WELLS FARGO & COMPANY/MN | 72971 | AGIOS PHARMACEUTICALS INC | COM | 00847X104 | 58 | 1979 | SH | DFND | 15 | 0 | 0 | 1979 | May 17th, 2022 01:24AM | May 17th, 2022 01:24AM | Agios Pharmaceuticals | Health Care | Pharmaceuticals & Biotechnology | |
| nasdaq:agio | nasdaq:agio Shareholders | 13F-HR | 0000072971-22-000135 | Mar 31st, 2022 12:00AM | May 16th, 2022 12:00AM | May 16th, 2022 12:00AM | WELLS FARGO & COMPANY/MN | 72971 | AGIOS PHARMACEUTICALS INC | COM | 00847X104 | 6 | 215 | SH | DFND | 13 | 0 | 0 | 215 | May 17th, 2022 01:24AM | May 17th, 2022 01:24AM | Agios Pharmaceuticals | Health Care | Pharmaceuticals & Biotechnology |